
Sneha Sudha Komath
Professor
Centre/School/Special Centre
School of Life Sciences
Room No
406
Off. Phone
011-26704502
Email
sskomath@mail.jnu.ac.in
Personal Webpage
Qualifications
Ph.D. University of Hyderabad (Hyderabad), India - 1999
M.Sc. (Chem.) University of Hyderabad (Gold Medalist) - 1991
Areas of Interest/Specialization
Glycobiology/ Biophysical Chemistry
Experience
2014-present Professor, School of Life Sciences, JNU
2008-2014 Associate Professor, School of Life Sciences, JNU
2003-2008 Assistant Professor, School of Life Sciences, JNU
1999-2002 Lecturer, Department of Chemistry, Panjab University, Chandigarh
2001-2002 Research Associate, University of Wisconsin, Madison, USA (on leave from PU).
1998-1999 Research Associate, Institute of Microbial Technology, Chandigarh.
1993-1998 UGC-JRF/SRF, School of Chemistry, University of Hyderabad.
1991-1993 UGC-JRF, SSCU, Indian Institute of Science, Bangalore.
Awards & Honours
National Women Bioscientist Award, 2010
Best Peer Reviewed Publications
- Yadav B, Bhatnagar S, Ahmad MF, Jain P, Pratyusha VA, Kumar P, Komath S.S. * 2014. First step of glycosylphosphatidylinositol (GPI) biosynthesis cross-talks with ergosterol biosynthesis and Ras signaling inCandida albicans. J Biol Chem. 289(6):3365-82. doi: 10.1074/jbc.M113.528802. Epub 2013 Dec 19.
- Ashraf M, Sreejith P., Yadav U. and Komath S. S. *. 2013 Catalysis by N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase (PIG-L) from Entamoeba histolytica: New roles for conserved residues. J. Biol. Chem. 288:7590-7595. doi: 10.1074/jbc.M112.427245. Epub 2013 Jan 22.
- Victoria G.S., Yadav B., Hauhnar L., Jain P., Bhatnagar S. and Komath S.S.*. 2012. Mutual Co-Regulation Between GPI-N-acetylglucosaminyl Transferase and Ergosterol Biosynthesis in Candida albicans. Biochem. J. 443(3):619-25. (Identified by the Target Selection Group of Global Medical Discovery as a paper of particular interest for drug discovery: http://globalmedicaldiscovery.com/key-scientific-articles)
- Ahmad M. F., Yadav B., Kumar P., Puri A., Mazumder M., Ali A., Samudrala S., Muthuswami R., and Komath S. S. *. 2012. The GPI anchor signal sequence dictates the folding and functionality of the ALS5 adhesin from Candida albicans. PLoS One 7(4):e35305. (Identified by the Target Selection Group of Global Medical Discovery as a paper of particular interest for drug discovery:http://globalmedicaldiscovery.com/key-scientific-articles)
- Ashraf M., Yadav B., Sreejith, Kumar K. S., Vats D., Muthuswami R. and Komath S. S.*. 2011. The N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase from Entamoeba histolytica: Metal alters catalytic rates but not substrate affinity. J. Biol. Chem. 286: 2543-2549
Recent Peer Reviewed Journals/Books
- Yadav B, Bhatnagar S, Ahmad MF, Jain P, Pratyusha VA, Kumar P, Komath S.S. * 2014. First step of glycosylphosphatidylinositol (GPI) biosynthesis cross-talks with ergosterol biosynthesis and Ras signaling inCandida albicans. J Biol Chem. 289(6):3365-82. doi: 10.1074/jbc.M113.528802. Epub 2013 Dec 19.
- Ashraf M, Sreejith P., Yadav U. and Komath S. S. *. 2013 Catalysis by N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase (PIG-L) from Entamoeba histolytica: New roles for conserved residues. J. Biol. Chem. 288:7590-7595. doi: 10.1074/jbc.M112.427245. Epub 2013 Jan 22.
- Komath S. S.*, Ahmad F. A. and Mazumder M. 2013. Cloning, expression and functional characterization of Als5, an adhesin from Candida albicans. Protein Purification and Analysis – Methods and Applications. ISBN: 978-1477555-05-7. iConcept Press. (Book Chapter)