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Vijay Kumar Goel

Vijay Kumar Goel

Vijay Kumar Goel
Vijay Kumar Goel
Associate Professor
Centre/School/Special Centre
School of Physical Sciences
Room No
326 (Lab# 320)
Off. Phone
+91-11-26739198
Email
vijaykgoel@mail.jnu.ac.in, vijaykgoel@jnu.ac.in
Personal Webpage
https://jnu.ac.in
Qualifications

Ph. D. (2005) Structure-Based Drug-Design, Department of Biophysics, All India Institute of Medical Sciences (AIIMS), New Delhi

Areas of Interest/Specialization

Structure-Based Drug-Design,
Peptide Chemistry,
Synthetic Organic Chemistry,
Nanotechnology,
X-Ray Crystallography

Experience

Associate Professor (Chemistry) - School of Physical Sciences, JNU (Since January 2021)
Assistant Professor (Chemistry) - Swami Shraddhanand College, Delhi University, Delhi (2015 - 2021)
Senior Manager - Bioconcept Labs Pvt. Ltd, Manessar, Haryana (2013 - 2014)
Senior Scientist and Head - Peptide Therapeutics Research Laboratory, Onestream Research Centre (DSIR), Panacea Biotec Ltd, New Delhi (2008 - 2013)
Young Scientist (DST) - Institute of Nuclear Medicine and Allied Sciences (INMAS), DRDO, New Delhi (2006 - 2007)
Scientist B - Medicinal and Process Chemistry Division, Central Drug Research Institute (CDRI), Lucknow (2005 - 2006)

Awards & Honours

Young Scientist Award (2006), Department of Science and Technology (DST), New Delhi
Post Doctoral Fellowship (2007), Dartmouth College, Hanover, New Hampshire, United States

International Collaboration/Consultancy

-

Best Peer Reviewed Publications
  1. Synthesis of Specific SPECT-Radiopharmaceutical for Tumor Imaging Based on Methionine: 99mTc-DTPA-bis (methionine);  Puja Hazari, Gauri Shukla, Vijay Goel, Krishna Chuttani, Nitin Kumar, Rajnish Sharma and Anil Mishra; Bioconjugate Chemistry 21(2)(2010) 229-239
  2. Effects of branched beta carbon dehydro residues on peptide conformation: Syntheses, crystal structures and molecular conformations of Cbz-DIle-Ala-DPhe-Ala-OCH3 and Cbz-DVal-Leu-DPhe-Leu-OCH3; V. K. Goel, R. K. Somvanshi, S. Dey and T. P. Singh, J. Peptide Res. 66(2) (2005) 68
  3. Design of peptides with a, b - dehydro residue: Crystal Structure and Molecular conformation of (i) Boc-Leu-DPhe-Leu-OCH3 and (ii) Boc-Ala-DPhe-Ala-OCH3.; V. K. Goel, S. Dey, R. K. Somvanshi and T. P. Singh; Structural Chemistry 16(4) (2005) 385-389
  4. Design of peptides with alpha-beta dehydro residue: Synthesis, Crystal Structure and Molecular conformation of Cbz-DVal-DPhe-Ala-OCH3. V. K. Goel, S. Dey and T. P. Singh, J. Mol. Struct. 738 (2005) 189-192
  5. Design rules for peptides with a, b - dehydro-residues: Synthesis of a model peptide Boc-Ile-DAla-OCH3 and its crystal structures obtained from two different solvents.; S. Dey, R. Vijayaraghavan, V. K. Goel, S. Kumar, P. Kumar, and T. P. Singh; J. Mol. Struct. 737 (2005) 109-116.
  6. Design of peptides with alpha-beta dehydro residue: Crystal Structure and Molecular conformation of Boc Phe-DPhe-Ile-OCH3 R, Vijayaraghavan, V. K. Goel, S. Dey, and T. P. Singh; Structural Chem. 16(4) (2005) 445-452
  7. Design of peptides with alpha-beta dehydro residue: Crystal Structure and Molecular conformation of Boc-Ala-DPhe-DPhe-Phe-OCH3 R. K. Somvanshi, V. K. Goel, S. Dey and T. P. Singh; J. Chem. Cryst. 35 (2005) 761-768
  8. Crystallographic analysis of 9-(3-methylbut-2-enyloxyfurano) [3,2-g] benzopyran-2-one; Rajnikant, Dinesh, A. S. Shawl, T. P. Singh, V. K. Goel and Bandhan Sharma; Journal of Chemical Crystallography, 35 (2005) 913-916
  9. Design of peptides with a, b - dehydro-residues: Crystal Structure of Boc-Leu-DPhe-Ile-OCH3, C27H43N3O7; V. K. Goel, M. Guha, A. P. Baxla, S. Dey and T. P. Singh; J. Mol. Struct. 658 (2003) 135-141.
Recent Peer Reviewed Journals/Books
  1. Kanika D, Chandra A, Kumar V, Othayoth J, Rathi B and Goel VK. Identification of Novel Peptide Inhibitors of Plasmodium falciparum Dihydrofolate Reductase (PfDHFR): Molecular docking and MD Simulation Studies, Journal of Biomolecular Structure and Dynamics, 2024, DOI:10.1080/07391102.2024.2335288
  2. Colaco V, Goswami N, Goel VK, et al. In silico and structure-based evaluation of deleterious mutations identified in human Chk1, Chk2, and Wee1 protein kinase. J Cell Biochem. 2024;125(1):89-99. doi:10.1002/JCB.30508
  3. Shukla R, Chandra A, Kumar A, et al. Repurposing of drugs against methyltransferase as potential Zika virus therapies. Scientific Reports 2023 13:1. 2023;13(1):1-15. doi:10.1038/s41598-023-33341-6
  4. Abdullahi M, Uzairu A, Shallangwa GA, et al. Molecular modelling studies of substituted indole derivatives as novel influenza a virus inhibitors. J Biomol Struct Dyn. Published online 2023. doi:10.1080/07391102.2023.2280735
  5. Jee B, Sharma PP, Goel VK, Kumar S, Singh Y, Rathi B. Natural Metabolite Ursolic Acid as an Inhibitor of Dormancy Regulator DosR of Mycobacterium tuberculosis : Evidence from Molecular Docking, Molecular Dynamics Simulation and Free Energy Analysis . Curr Comput Aided Drug Des. 2023;19(6). doi:10.2174/1573409919666230201100543
  6. Kherwal M, Gupta A, Jacob M, et al. Recent advances in self-assembled cyclic peptide-based smart nano-structures. Applied Chemical Engineering. 2023;6(1). doi:10.24294/ace.v6i1.1989
  7. Sharma R, Borah SJ, Bhawna, et al. Functionalized Peptide-Based Nanoparticles for Targeted Cancer Nanotherapeutics: A State-of-the-Art Review. ACS Omega. 2022;7(41). doi:10.1021/acsomega.2c03974
  8. Abdullahi M, Uzairu A, Shallangwa GA, et al. In-silico molecular modelling studies of some camphor imine based compounds as anti-influenza A (H1N1) pdm09 virus agents. J Biomol Struct Dyn. Published online 2024. doi:10.1080/07391102.2023.2209654
  9. Sharma PP, Bhardwaj S, Sethi A, et al. Chitosan based architectures as biomedical carriers. Carbohydr Res. 2022;522. doi:10.1016/j.carres.2022.108703
  10. Sharma PP, Bansal M, Sethi A, et al. Computational methods directed towards drug repurposing for COVID-19: advantages and limitations. RSC Adv. 2021;11(57):36181-36198. doi:10.1039/D1RA05320E
Patents (if any)

"TUMOR NECROSIS FACTOR ALPHA INHIBITING PEPTIDES AND USES THEREOF" International Publication Number: WO 2010/058419 A1; Assignee: Panacea Biotec Pvt Ltd.; Inventors: Rajesh Jain, V. K. VInayak, Sudhanand Prasad, Shweta Dubey, Vijay Goel and Rahul Jain; US Patent App. 13/130,267

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.